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Traversing Geodesics in Discovery-Development Space from Novel Electrophotocatalysis to Sustainable and Scalable Manufacturing Processes

AN EXCITING COLLABORATIVE PROJECT

Part of the 27th Competitive Research Project (CRP) grant call by National Research Foundation (NRF)

Objective

Pharmaceutical, agrochemical, and fine chemical manufacturers in Singapore, contributing significantly to the country's GDP, are responding to global demand and government regulations by shifting towards greener, safer, and more cost-effective chemical production processes. Currently, these industries rely on thermal energy for traditional chemical processes. This research project aims to revolutionize this approach by harnessing solar energy and electricity to drive innovative processes based on single electron transfer (SET) events.

Our goal is to design electrophotocatalytic methods for precise control of electrons and ions, enabling the synthesis of various pharmaceutical and agrochemical ingredients. To expedite sustainable manufacturing, the project also plans to develop new workflows, including high-throughput screening and advanced reactor designs, combining expertise in chemistry, engineering, modeling, and data science. This multidisciplinary effort benefits from strong collaborations with the industry partner Syngenta.

Featured Publications

Sustainable electrocatalytic oxidation of N-alkylamides to acyclic imides using H₂O

Jing Qi, Xiyan Wang, Gan Wang, Srinivas Reddy Dubbaka, Patrick O'Neill, Hwee Ting Ang, Jie Wu.

Green Chem. 202426, 306-311. DOI: https://doi.org/10.1039/D3GC04010K

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