Current Projects | Chiba Research Group

Current Research Interests

Synthetic photo− and electrochemistry

Our group is currently interested in the active utilization of solar (visible light) energy and electricity to create innovative process technologies driven by single electron transfer (SET) events. We are currently studying a potent photocatalytic system employing readily accessible and inexpensive polysulfide anions, which are actively employed as the charge transfer carriers in the lithium−sulfur batteries. In addition, our group is currently leading a multi−disciplinary research team spanning synthetic organic chemistry, catalysis, electrochemistry, photochemistry, materials chemistry, computational modeling, and chemical engineering with an industry partner, Syngenta, through the NRF CRP project on the development of novel electrophotocatalysis for the greener and more sustainable manufacturing of complex small molecules. For in-depth details of this project, visit our website below:

NRF CRP Project

Main group metal hydrides

Our team recently introduced a simple method to activate NaH via solvothermal treatment in the presence of NaI or LiI in THF. We are currently focused on utilizing NaH as a powerful source of hydrides, enabling the creation of other main group metal hydrides from easily accessible main-group metal halides. Additionally, we unveiled the unique hydridic reactivity of magnesium hydride (MgH₂), generated in situ by exchanging counter ions between NaH and magnesium iodide (MgI₂) in THF. This reactive species exhibits distinct behavior with non-polar π-conjugated systems. The resulting organomagnesium reagents, akin to Grignard reagents, offer concise pathways for downstream functionalization with various electrophiles. This approach facilitates the construction of valuable synthons in a highly efficient manner.

Synthesis of complex molecules

Natural and unnatural products bearing complex molecular structures, potent biological activity, and unique functions for materials−based application always stimulate us to challenge their efficient synthesis. Our group is also involved in Master Research Collaboration Agreement with Nanyang Biologics Pte Ltd., in which we are closely working with cancer biologists toward the development of small molecule anti−cancer drugs based on the lead natural products isolated from the tropical herb plants and synthesized/derivatized by us.